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Keeping in mind the events of each part of the cell cycle, describe where cells might exit the cell cycle...

Question 21
Keeping in mind the events of each part of the cell cycle, describe where cells might exit the cell cycle to G0. Why did you choose this location? (Hint: Think of a place where the cell functions normally, but isn't preparing to divide.)
Question 22
Consider a cell in G0. Use information from Models 1 & 2 to answer:
a. In order for this cell to divide normally, what would need to occur?
b. What if the phase(s) identified in part (a) did not occur? What would be the outcome?

Answer

Question 21: Cells might exit the cell cycle to G0 after the G1 phase. This is because, during G1, the cell grows and carries out normal functions but is not yet committed to DNA replication. Exiting to G0 at this point allows the cell to function normally without preparing for division.

Question 22:

  1. a. To divide normally, the cell would need to re-enter the cell cycle, specifically the G1 phase, and proceed through the checkpoints to ensure it is ready for DNA replication and division.
  2. b. If the cell does not re-enter the cell cycle from G0, it will remain in a non-dividing state, potentially leading to tissue maintenance without proliferation. If necessary phases are skipped, it could result in incomplete or abnormal cell division.

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