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Math Asked by a SnapAndSolve user · about 19 hours ago

What is priming the MDI? When should it be done?

23. What is priming the MDI? When should it be done?
24. What other substances are found in MDIs that may produce clinical problems?
25. What percentage of the drug in an MDI is actually deposited in the lungs? Why is there so much variability?
26. Describe the proper technique for open-mouth MDI delivery in order:
A. Hold your breath for 10 seconds.
B. Breathe out normally.
C. Wait 1 minute.
D. Actuate the canister.
E. Hold the MDI two fingers from mouth.
F. Slowly inhale as deeply as you can.
G. Warm and shake the canister.
H. Actuate the canister (prime).
I. Take off the cap.
27. What is the difference between a spacer and a holding chamber? Does it matter?
28. Holding chambers are especially useful for what class of inhaled medications?
29. How does the recommended breathing pattern with a holding chamber differ from that with a spacer or using a mouthpiece?

Answer

  1. Priming the MDI involves releasing a few test sprays into the air to ensure the inhaler is working properly and delivering the correct dose. It should be done before the first use and if the inhaler hasn't been used for a while.

  2. Other substances in MDIs may include propellants and preservatives, which can cause irritation or allergic reactions in some patients.

  3. Percentage of drug deposited in the lungs from an MDI is typically around 10-20%. Variability is due to factors such as inhaler technique, particle size, and individual patient differences.

  4. Proper technique for open-mouth MDI delivery:

    1. Take off the cap.
    2. Warm and shake the canister.
    3. Hold the MDI two fingers from mouth.
    4. Breathe out normally.
    5. Slowly inhale as deeply as you can.
    6. Actuate the canister.
    7. Hold your breath for 10 seconds.
    8. Wait 1 minute.

  5. Difference between a spacer and a holding chamber: A spacer is a simple tube that adds space between the MDI and the mouth, while a holding chamber has a one-way valve to hold the medication until inhalation. Holding chambers are generally more effective in ensuring medication delivery.

  6. Holding chambers are especially useful for corticosteroids to reduce inflammation in the airways.

  7. Breathing pattern with a holding chamber involves slow, deep breaths to ensure medication is inhaled properly, whereas a spacer or direct MDI use may require faster inhalation to coincide with the actuation of the inhaler.

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